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AN ANTIMICROBIAL ANALYSIS AND PHYTOCHEMICAL OF Mangifera indica AND Carica papaya LEAVES
BACKGORUND TO THE STUDY: It is well known that in order for a plant to protect itself, it creates certain compounds that can also protect humans from sickness. Today, there are approximately 4000 distinct phytochemicals that have the potential to alter disorders such as cancer, stroke, or the metabolic system (Arts and Hollman, 2005). Phytochemicals are naturally occurring chemical substances in plants that are responsible for numerous plant characteristics such as smell, tas...
View DetailsASSESSMENT OF THE MATERIAL COMPOSITION USED IN CANDLE PROCESSING AND PRODUCTION
INTRODUCTION: Candles are derived from the Latin word "candera," which roughly translates to "to shine." Candles were the only source of artificial light prior to the development of electricity. The original candles were made of tallow, followed by beeswax and whale oil until paraffin, soy, and other vegetable-based waxes became popular in recent years. The candle is defined poetically in the 1738 Universal Lexicon as "a wick of...
View DetailsCYTOLOGICAL EVALUATION OF SPUTUM SAMPLES IN WELDERS IN OWERRI METROPOLIS
INTRODUCTION: Welding process involves joining metal parts by heating the pieces to melting temperature (Kimet et al., 2005). Soldering process as a type of welding produces various contaminants at a sufficient rate to cause both short term and long term health effects, especially if not properly controlled (Antonini et al., 1998). The metal composition of the generated fume during welding of metals is mostly dependent on the welding electrode or wire which...
View DetailsCHEMICAL ANALYSIS OF DETTOL PRODUCTION
ABSTRACT: Dettol is non-poisonous, safe, pleasant and economical in use. It has an agreeable smell. Dettol is active against both germ positive and Germ negative micro-organisms. It is well tolerated on the skin and tissues in high concentration. The original Dettol liquid antiseptic and disinfectant is light yellow in colour in the concentrated form. Bacteriological data and the literature of Dettol are available on request. Antibacterial are antiseptics that have the p...
View DetailsAN EVALUATION OF SOME CHEMICAL CONSTITUENTS OF SELECTED ENERGY DRINKS
ABSTRACT: This research work examined and compares the physicochemical properties and some chemical constituents of selected energy drinks. Fourteen (14) brands of energy drinks samples consisting eleven (11) liquid and three (3) powdered forms were randomly purchased. All samples were analyzed for their physicochemical properties (pH, turbidity, conductivity and total dissolved solids), trace and heavy metals, aspartame, sugar and caffeine contents. Results showed that the p...
View DetailsTHE MATERIAL COMPOSITION IN THE PROCESSING OF CANDLE PRODUCTION
CHAPTER ONE
INTRODUCTION: The word candle is derived from the Latin word "candera," which roughly translates to mean "to shine." Before the invention of electricity, candles were the only source of artificial light. The first candles were made from tallow, and then they were fashioned from beeswax and whale oil before paraffin, soy, and other vegetable-based waxes...
View DetailsTHE ECONOMIC IMPORTANCE OF FERMENTATION
CHAPTER ONE
Introduction: Fermentation is the chemical transformation o organic substances into simpler compounds by the action of enzymes, complex organic catalysts which are produced by microorganisms such as molds yeasts or bacterial. Enzymes act by hydrolysis a process of breaking down or predigesting complex organic molecules for form smaller (and in the case foods, more easily digestible) compounds and nutrients for example, the enzyme proteas...
View DetailsThe Role of Alpha Lipoic Acid and Olive Oil on Metabolic Syndrome Associated with Letrozole-induced Polycystic Ovarian Syndrome
INTRODUCTION
A prevalent reproductive endocrine disorder called polycystic ovarian syndrome (PCOS) affects 5–10% of females who are of reproductive age. Over 116 million women globally, according to estimates from the World Health Organization (WHO), have PCOS. Hyperandrogenism, anovulatory infertility, irregular menstruation, and metabolic abnormalities such obesity, insulin resistance (IR), hyperinsulinemia, dyslipidemia, and glucometabolic diseases are some...
View DetailsGAS CHROMATOGRAPHY- MASS SPECTROMETRY ANALYSIS AND EFFECT OF Amaranthus hybridus AQUEOUS LEAF EXTRACT ON PLASMA AND HEART LIPID PROFILE IN DOXORUBICIN INDUCED CARDIOTOXIC RAT
INTRODUCTION: Doxorubicin poisoning has been linked to organ damage, particularly the heart (Indu et al., 2014; Afsar et al, 2017; Zilinyi et al., 2018; Ahmed et al., 2019). A variety of pathways for doxorubicin-induced cardiotoxicity have been proposed in numerous research. Among those implicated are oxidative stress, inflammation, apoptosis, protein synthesis inhibition or abnormal protein processing, mitochondrial abnormalities, and lysosomal alterations (Abdalla et al., 2...
View DetailsEFFECT OF Phyllanthus amarus AND N-HEXADECANOIC ACID ON BLOOD COAGULATION PARAMETERS OF LIPOPOLYSACCHARIDE-INDUCED INFLAMMATION IN WISTAR RATS
ABSTRACT
Blood clotting is a complex sequence of processes involving multiple proteins (factors) that must operate in a specific order to create a clot. The procedure is rapid and effective, but it must be monitored because uncontrolled clotting can lead to thrombosis. A shift in the balance of blood coagulation and coagulation inhibition, favoring either pro- or anticoagulation, can result in life-threatening thromboembolism or bleeding. This study evaluated the effect of ethanol P...
View DetailsMODULATORY EFFECT OF METFORMIN AND ARTEMETHER-LUMEFANTRINE ON BLOOD COAGULATION IN DIABETIC MICE CO-INFECTED WITH MALARIA
ABSTRACT
Blood coagulation is a process describing conversion of soluble materials within the blood into an insoluble gel that plugs injury/break site within blood vessels; this process requires regulation. Diabetes mellitus is a metabolic disorder characterized by hyperglycemia, defectiveness of insulin hormone has been found to have an increased risk of coagulation and can lead to cardiovascular disorders. Malaria is a disease caused by plasmodium parasite, when the parasite enter...
View DetailsMOLECULAR CHARACTERIZATION OF PATHOGENIC ESCHERICHIA COLI IN READY-TO-EAT GAME MEAT AND FRESH PRODUCE FROM SOUTHWESTERN REGION OF NIGERIA
ABSTRACT
The consumption of ready-to-eat (RTE) game meat and fresh produce has increased and it serves as a very important part of human diet. Foodborne diseases linked to contaminated RTE game meat and fresh produce is a public health concern. This study investigated the pathogenic E. coli in these RTE foods sold in various cities in south western, Nigeria. The identification of E. coli were performed using sorbitol MacConkey agar (SMAC) and molecular characterization of virulence...
View DetailsIN SILICO EVALUATION ON THE INTERACTION BETWEEN KETONE BODIES AND OBESITY-ASSOCIATED PROTEINS
Background of study
Obesity, has been a pre-existing problem afore time but has been recognized as a global pandemic since the 21st century (Natalia, et al., 2021). Aronne, 2002 defines obesity as the anomalous, irregular or disproportionate gain of weight as a result of fat buildup in the body which adversely leads to the risk of several health related problems such as hypertension, type 2 diabetes, cardiovascular diseases and certain cancer types amongst others (Aronne, 2002; Nata...
View DetailsAN INVESTIGATION INTO THE HEALTH DANGER OF POTASSIUM BROMATE CONTENT IN BREAD SAMPLES (A CASE STUDY OF ENUGU METROPOLIS)
CHAPTER ONE
INTRODUCTION
Bread is an important source of food prepared by cooking dough of flour and water, and possibly more ingredients. Dough is usually baked but in some cuisines, breads are steamed, fried or baked on an unoiled skillet. It may be leavened or unleavened salt, fat and leavening agents such as yeast and baking soda are common ingredients. Though bread usually contains several ingredients that would help improve the qual...
View DetailsISOLATION AND PROPAGATION OF LACTIC ACID BACTERIA FROM FERMENTED MAIZE FLOUR FOR THE OPTIMIZATION OF THE FERMENTATION PROCESS
GENERAL ABSTRACT
Production of traditional fermented foods especially lactic acid fermented foods has long been practiced for ages in Africa with a variety of products being produced. Lactic fermentation improves the digestibility of proteins and starch, bioavailability of micronutrients, palatability of porridges as well as imparting antimicrobial properties in...
View DetailsPHYSICOCHEMICAL PROPERTIES OF GROUNDNUT OIL AND PALM OIL IN OGBOMOSO SOUTH LGA, OYO STATE
PHYSICOCHEMICAL PROPERTIES OF GROUNDNUT OIL AND PALM OIL IN OGBOMOSO SOUTH LGA, OYO STATE
Table of Contents
Chapter 1: Introduction
1.1 Background of the Study
1.2 Statement of the Pro...
View DetailsA Comparative Study Of Chemical And Microwave Synthesized Activated Carbon From carbon Carbon
1.1BACKGROUND OF STUDY
Activated carbon, also widely known as activated charcoal or activated coal is a form of carbon which has been processed to make it extremely porous and thus to have a very large surface area available for adsorption or chemical reactions (Mattson et al., 1971). The word active is sometimes used in place of activated. It is characterized by high degree of micro porosity. A gram of activated carbon can have a surface area in excess of 500 m2. Sufficient activat...
View DetailsANTI-HYPERLIPIDEMIC POTENTIAL OF VITEX DONIANAETHANOLEXTRACTS ON POLOXAMER 407 INDUCED HYPERLIPIDEMIC AND NORMAL RATS.
ABSTRACT
Anti-hyperlipidemic potential of extracts (aqueous, 70% methanol, 70% ethanol and 70%, acetone) of Vitexdoniana leaves, stem bark and root bark on poloxamer 407 induced hyperlipidemic and normal rats was investigated. Phytochemical screening of the extracts revealed the presence of flavonoids, saponins, cardiac glycosides, alkaloids and tannins in the leaves, stem bark and root bark. The average total polyphenol contents of the leaves ethanol (36.11±3.13mg/g gallic a...
View DetailsANTILIPIDEMIC EFFECT OF WATER (H20) EXTRACT OF DESMODIUM VELUTINUM LEAVES ON ALBINO WISTAR RATS
ABSTRACT
This study evaluated the antilipidemic activity of water extracts from leaves of Desmodium velutinum on albino wistar rats. The phytochemical analysis of the leaf extract showed the presence of tannins, saponins, alkaloids, soluble carbohydrates, flavonoids, reducing sugar, steroids, cyanide and terpenoids. The animals were treated with known drugs (atorvastatin 2ml). There were significantly reductions in HDL 13.00 1.41 mg/dl LDL 1.20
0.14 mg/dl and t...
View DetailsASSESSMENT OF VARIOUS BIOCHEMICAL CHANGES IN HYPERTENSIVE AND HYPERTENSIVE-PRONE ADULT NIGERIANS IN JOS, NIGERIA
ABSTRACT
A total of 1,075 fasting Human Serum and early morning urine samples were assayed for various biochemical parameters. The parameters include: Blood lipids, Total Cholesterol, High Density lipoproteins, Low Density lipoproteins, Vitamin A, Sodium, Potassium, Chloride, Bicarbonate, Urinary glucose, Protein and Blood.
From the results obtained, the calculated phospholipids:cholesterol ratio was less than 1 amongst the hypertensives. This confirmed the work of Stroev...
View DetailsCARDIO PROTECTIVE ACTIVITIES OF N-HEXANE EXTRACT OF DESMODIUM VELUTINUM STEM ON ALBINO WISTER RAT
ABTRACT
This study evaluates the cardio protactive effect of N-hexane extract of Desmodium Velutinum stem on albino wister rat. Rats used in this study were grouped into four and each group was fed differentely. Rats in group one, three, and four wre fed with the aid of a syringe without needle with 6ml of the lipoprotein food mixture containing 3.6g of the cow’s brain twice a day for seven days. Rats on group two was fed with only grower’s mash and water for seven days;...
View DetailsDETERMINATION OF ACTIVE SWEET COMPONENTS OF COMMON ARTIFICIAL SWEETENERS THAT ARE USED AS REPLACEMENT FOR SUGAR
ABSTRACT
This research investigated how the sweetness of sugar substitute compares to the sweetness of sugar. In this research different percentage solution of sugar, artificial sweetener and natural sweetener (10%, 1%, 0.1% and 0.01%) were prepared. Ten volunteers were gathered for the sensory evaluation in this case tasting of the solution, the volunteer‟s taste threshold of data was gotten. The artificial sweetener was found out to be the sweetest among the substances experimente...
View DetailsEFFECT OF GLYCEROL AND SHEA BUTTER ON THE PROPERTIES OF FILMS PRODUCED FROM CHITOSAN AND Borassus aethiopum STARCH COMPOSITES
ABSTRACT
The concern in environmental waste management and toxicity of petroleum derived plastics has led to the search for renewable, nontoxic and biodegradable materials for packaging. Starch is the most studied and promising biopolymer for the production of biodegradable films, but this starch films have poor properties which can be improved by blending with other materials and plasticizers. Borassus aethiopum shoot starch locally known as “Muruci” is a promising film...
View DetailsELEMENTAL ANALYSIS ON PTEROCARPUS MILDBREADII (OHA)SEED
ABSTRACT
Elemental analysis is the qualitative detection and quantitative determination of chemical elements(atoms,ions)in a sample(Fritz Pregl 1923). To detect an
element, one should fix an appearance of an analytical signal. The formation of precipitate or characteristic crystals, colour change, an isolation of gaseous products, an appearance of a definite lines in spectrum, luminescence, etc. To determine elements quantity, it is necessary to measure a value of an analy...
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