AN ANTIMICROBIAL ANALYSIS AND PHYTOCHEMICAL OF Mangifera indica AND Carica papaya LEAVES
BACKGORUND TO THE STUDY: It is well known that in order for a plant to protect itself, it creates certain compounds that can also protect humans from sickness. Today, there are approximately 4000 distinct phytochemicals that have the potential to alter disorders such as cancer, s...
View DetailsTHE PHYSICO-CHEMICAL AND ANTIOXIDANT PROPERTIES OF CULINARY HERBS AND LOCAL SPIES
CHAPTER ONE
INTRODUCTION
Herbs and spices have long been used by ancient civilsations for culinary, medicinal and cosmetic uses. With modernization and the development of patent medicines, the use of natural cures and elixirs decrease in popul...
View DetailsThe Role of Alpha Lipoic Acid and Olive Oil on Metabolic Syndrome Associated with Letrozole-induced Polycystic Ovarian Syndrome
INTRODUCTION
A prevalent reproductive endocrine disorder called polycystic ovarian syndrome (PCOS) affects 5–10% of females who are of reproductive age. Over 116 million women globally, according to estimates from the World Health Organization (WHO), have PCOS. Hy...
View DetailsGAS CHROMATOGRAPHY- MASS SPECTROMETRY ANALYSIS AND EFFECT OF Amaranthus hybridus AQUEOUS LEAF EXTRACT ON PLASMA AND HEART LIPID PROFILE IN DOXORUBICIN INDUCED CARDIOTOXIC RAT
INTRODUCTION: Doxorubicin poisoning has been linked to organ damage, particularly the heart (Indu et al., 2014; Afsar et al, 2017; Zilinyi et al., 2018; Ahmed et al., 2019). A variety of pathways for doxorubicin-induced cardiotoxicity have been proposed in numerous research. Amon...
View DetailsEVALUATION OF BERRY EXTRACTS ON INTESTINAL DIGESTIVE ENZYMES AND SUGAR TRANSPORTERS
ABSTRACT
Diabetes mellitus affects over 8% of the world population, with the great majority having type 2 diabetes mellitus (T2DM). T2DM is characterized by postprandial hyperglycemia and has been identified as key causes of morbidity and mortality with...
View DetailsAMELIORATIVE EFFECT OF RESVERATROL ON LEAD-INDUCED ORGAN TOXICITY IN WISTAR RATS
ABSTRACT
Resveratrol is a potent antioxidant found abundantly in grapes and in lesser quantities in peanuts, fruits and other food items. Dozens of reports have shown that resveratrol prevents or slows the progression of a wide variety of illnesses including cancer (colon and melanoma)....
View DetailsAN EVALUATION OF THE APHRODISIAC AND FERTILITY ENHANCING EFFECT OF THE METHANOLIC ROOT EXTRACT OF CISSUS POPULNEA Guill.And Perr. (Vitaceae)
ABSTRACT
Aphrodisiac activity of Cissus populnea was assessed using physical, biochemical and psychological methods. Rats were randomized into five groups of six rats. The first group received normal saline (10ml/kg), the second, third and fourth groups received extract doses of 250mg/k...
View DetailsANALYSIS OF PETROLEUM POLLUTION ON SERUM TRACE ELEMENT LEVEL, OXIDATIVE STATUS, AND BIOCHEMICAL INDICES IN THE RESIDENTS OF AN OIL HOST COMMUNITY (UGBEGUNGUN) IN DELTA STATE, NIGERIA
ABSTRACT
Activities of crude oil refining disrupt natural ecosystems which expose residents to environmental pollution, and consequently pose threat to their health and wellness. This study was aimed to analyze serum trace elements levels, oxidative status, and biochemical indices in th...
View DetailsANTI-HYPERLIPIDEMIC POTENTIAL OF VITEX DONIANAETHANOLEXTRACTS ON POLOXAMER 407 INDUCED HYPERLIPIDEMIC AND NORMAL RATS.
ABSTRACT
Anti-hyperlipidemic potential of extracts (aqueous, 70% methanol, 70% ethanol and 70%, acetone) of Vitexdoniana leaves, stem bark and root bark on poloxamer 407 induced hyperlipidemic and normal rats was investigated. Phytochemical screening of the extracts revealed the presenc...
View DetailsCHEMICAL AND BIOLOGICAL STUDIES OF HONEY BEE PROPOLIS COLLECTED FROM ZANGO KATAF LOCAL GOVERNMENT AREA OF KADUNA STATE, NIGERIA
ABSTRACT
Honeybee Propolis from Apis mellifera (Linn), has been used in ethno medicine as an emollient in the treatment of ringworm, measles, chickenpox and with reported biological activities, such as antitumor, antioxidant, immunomodulatory action and anti-inflammatory action among ot...
View DetailsEFFECT OF AQUEOUS ETHANOL LEAF EXTRACT OF COMBRETUM MICRANTHUM G. DON (COMBRETACEAE) ON SOME INDUCED SYSTEMIC INFLAMMATORY IMMUNE RESPONSE SYNDROMES IN MICE AND RATS
Abstract
The cellular immunity is often suppressed by infection, disease conditions and drug medication that are in continous association with mankind. Combretum micranthum is a plant known for its antioxidant, antimicrobial, anti-inflammatory and various other properties of immune boos...
View DetailsEFFECT OF MICRONUTRIENT SUPPLEMENTATION ON SOME INDICES OF HIV INFECTION PROGRESSION AMONG ANTIRETROVIRAL NAÏVE PATIENTS ATTENDING HIV CLINICS IN ZARIA AND KADUNA, NIGERIA
Abstract
Nigeria has the second highest HIV/AIDS burden in the world with an estimated 3,391,546 people living with HIV and AIDS; an estimated 239,155 people acquired new infections in 2013; and about 174,253 people died from AIDS related illness (s) in 2014. HIV infection causes a chro...
View DetailsEFFECTS OF VITAMIN B COMPLEX THERAPY ON TEMPORAL VARIATION IN GENTAMICIN NEPHROTOXICITY IN WISTAR RATS
ABSTRACT
The efficacy and toxicity of several drugs is circadian-rhythm dependent, and this can be exploited as a guide to ameliorate such drug toxicity. Gentamicin is an aminoglycoside antibiotic used in treatment of a variety of infections. Its use is however limited by its associated...
View DetailsEFFECTS OF VITAMIN B COMPLEX THERAPY ON TEMPORAL VARIATION IN GENTAMICIN NEPHROTOXICITY IN WISTAR RATS
ABSTRACT
The efficacy and toxicity of several drugs is circadian-rhythm dependent, and this can be exploited as a guide to ameliorate such drug toxicity. Gentamicin is an aminoglycoside antibiotic used in treatment of a variety of infections. Its use is however limited by its associated...
View DetailsEFFECTS OF WATER-SOLUBLE FRACTIONS OF USED CRANKCASE OIL ON SOME PHYSIOLOGICAL PARAMETERS OF THE NILE TILAPIA (OREOCHROMIS NILOTICUS)
ABSTRACT
Used crankcase oil is disposed off indiscriminately and it eventually finds its way into the aquatic environment resulting in surface and ground water contamination by complex interacting chemicals and substances. Polycyclic aromatic hydrocarbons (PAHs), heavy metals, additives...
View DetailsEVALUATION OF THE ANTIMICROBIA; ANTIOXIDANT AND STAINING PROPERTIES OF SIX INDIGENOUNS PLANTS EXTRACTS COLLECTED FROM SOUTHERN NIGERIA
1.0Background of Study
The Nigeria climate favours a great array of plant species many of which have varied medicinal and antimicrobial potentials (Adewusi, 1997; Adeuse-Poku et al., 2003; Ajebesone and Aina, 2004, Agyili et al., 2006). It is estimated that there are over 65,000 species...
View DetailsCOMPARISON BETWEEN AQUEOUS AND ETHANOLIC EXTRACTS OF VERNONIA AMYGDALINA ON FUNGAL AND BACTERIAL ISOLATE FROM SPOILED PEPPER AND TOMATO FRUIT IN DUTSE JIGAWA STATE
ABSTRACT
Post-harvest spoilage of fruits, particularly tomatoes and peppers, poses significant challenges to food security and economic sustainability in Nigeria. This study investigated the comparative antimicrobial efficacy of aqueous...
View DetailsTHE EFFECT OF ANTHRAQUINONE DERIVATIVES ON SERUM GAMMA-GLUTAMYL TRANSFERASE ACTIVITY IN HIGH-FAT DIET-INDUCED OBESITY IN WISTAR RATS
1.1 Background of the Study
Anthraquinones, a class of organic compounds often derived from plants and synthesized for medicinal purposes, have garnered significant interest for their wide-ranging biological activities, particularly as...
View DetailsPRODUCTION AND ANALYSIS OF LIQUID SOAP USING CLOVES EXTRACTS
1.1 Background of the Study
Liquid soaps have continue to see a growing demand among households and industries for various purposes. Cloves (Syzygium aromaticum) are antibacterial, antifungal, and antioxidant (Saeed & Tari...
View DetailsPRODUCTION AND QUALITY ASSESSMENT OF ZOBO DRINK
1.0 Background of the Study
Zobo drink, made from dried calyces of Hibiscus sabdariffa, is a popular and widely consumed beverage in many parts of the world, particularly in West Africa. The drink is known for its vibrant red color, ref...
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