BACKGORUND TO THE STUDY: It is well known that in order for a plant to protect itself, it creates certain compounds that can also protect humans from sickness. Today, there are approximately 4000 distinct phytochemicals that have the potential to alter disorders such as cancer, s...

ABSTRACT

Gongronema latifolium is an edible tropical rainforest plant traditionally used as a spice, staple vegetable and in the treatment and management of diabetes. Extensive studies have established its hypoglycaemic effect. However, scanty information is available on the mechanism b...

BACKGROUND OF STUDY

The healing effects of medicinal plants have been used to treat a number of human diseases for hundreds of years. Traditional herbal medicines are used by 60-90 percent of the population in developing countries, who consider them to be a part of primary healthcare (W...

INTRODUCTION: Doxorubicin poisoning has been linked to organ damage, particularly the heart (Indu et al., 2014; Afsar et al, 2017; Zilinyi et al., 2018; Ahmed et al., 2019). A variety of pathways for doxorubicin-induced cardiotoxicity have been proposed in numerous research. Amon...

ABSTRACT

The plant Andropogon gayanus is employed in herbal medicine for the treatment of various disease conditions. The dried root of the plant is soaked in milk and taken for the treatment of postpartum pain and bronchitis in North-west Nigeria. In this study the methanol root extrac...

ABSTRACT

The herbalists in several African Countries have used Rothmannia longiflora decoctions as febrifugal and analgesic agent. The present study examined the analgesic, anti-inflammatory and toxicological profile of the methanolic extract of the plant in experimental animals.

ABSTRACT

Synthetic analgesic and anti-inflammatory drugs have major side effects such as constipation, nausea and vomiting, sedation and mental clouding, etc.,which have significantly limited their use.There is therefore, an intensification of search for newer analgesic and anti-inflamm...

ABSTRACT

Curcuma longa are traditionally used for the treatment of ulcers, hepatic disorder, wound healing and boost glucose control. This study assessed the phytochemical compositions (quantitative and qualitative), antibacterial activities of C. longa crude extracts, synthesis and cha...

ABSTRACT

Medicinal plants contain active ingredients with therapeutic values. Helianthus annuus L (Asteraceae) commonly referred to as “sunflower” has been reportedly used in managing and treating some ailments over the years. This study investigated the in vitro and in vivo...

ABTRACT

Many bacterial species have been reported to develop resistance to antibiotics commonly prescribed for respiratory tract infections. Therefore, the need to search for natural products for remedy of this problem cannot be overemphasized.

One hundred and eighty (180) spe...

ABSTRACT

Diospyros mespiliformis hochst (Ebenaceae) known in English as ebony is a plant that is found throughout West Africa. The Plant was reported to have wide ethnomedical application notably in fever, whooping cough, wounds, pneumonia, syphilis, leprosy and epilepsy among others. T...

ABSTRACT

Cassia siamea is a shrub belonging to the Fabaceae family, native of Southeast Asia. The plant is commonly used in traditional medicine to treat hypertension, malaria and diabetes. Due to the easy cultivation of the plant, its widespread and also remarkable biological activitie...

ABSTRACT

LaggeraauritaLinn. belongs to the family of Asteraceae. It is an annual herb which is found growing as weeds in Nigeria and spread throughout the sub-Saharan Africa. In Nigeria, Laggeraaurita is used asa remedy for pediatric malaria and in the management of epilepsy in Niger st...

ABSTRACT

Diabetes mellitus and its complications continue to be one of the highest causes of morbidity and mortality in recent times. Although many drugs are commercially available for use in the management of diabetes, their side effects and high costs underscore the need for new drugs...

Abstract

Irvingia wombolu is one of the herbal plants used as food for its nutritional values. It is also used as medicinal plant in the south-south and south-eastern part of Nigeria for the management of diarrhoea and other ailments. Although these medicinal plants are believed to be h...

Abstract

The objective of the present study was to evaluate the antidiarrheal activity of the methanol stem bark extract of   Hymenocardia acida in some laboratory animals. They methanol stem bark extract of Hymenocardia acida (MEHA) was prepared from the freshly collected ste...

ABSTRACT

The plant Combretum hypopilinum has been used in traditional medicine to treat diarrhoea and other gastrointestinal diseases. This study aimed to investigate the antidiarrhoeal activity and toxicity profile of the methanol leaf extract of Combretum hypopilinum (MECH) in mice an...

ABSTRACT

Diabetes mellitus is a metabolic disorder which affects about 346 million people globally. Synthetic antidiabetic agents are expensive and also associated with side effects. In a bid to develop cheaper and safer antidiabetic agents, this study was carried out to determine the e...

ABSTRACT

Anti-hyperlipidemic potential of extracts (aqueous, 70% methanol, 70% ethanol and 70%, acetone) of Vitexdoniana leaves, stem bark and root bark on poloxamer 407 induced hyperlipidemic and normal rats was investigated. Phytochemical screening of the extracts revealed the presenc...

ABSTRACT

This study evaluated the antilipidemic activity of water extracts from leaves of Desmodium velutinum on albino wistar rats. The phytochemical analysis of the leaf extract showed the presence of tannins, saponins, alkaloids, soluble carbohydrates, flavonoids, reducing sugar, ste...

ABSTRACT

Malaria is one of the most debilitating tropical parasitic diseases and the greatest cause of hospitalization and death. Recurring problems of drug resistance are reinforcing the need for finding new antimalarial drugs. In this respect, natural plant products are the main sourc...

ABSTRACT

The treatment inadequacy and toxicity associated with conventional anti-malarial, anti- inflammatory and analgesic drugs calls for the search for alternatives from medicinal plants, particularly. In the present study, alkaloid fraction of Maytenus senegalensis leaf was evaluate...

ABSTRACT

The leaf of Mitracarpusvillosus (Sw.) DC. (Rubiaceae) is used in West African folk medicine for the management of a plethora of stress-related diseases including headaches and toothaches. In this study, preliminary phytochemical analysis of the ethylacetateleaf extract of Mitra...

1.1Background of the Study

Plants are important in our everyday existence. They provide our foods, produce the oxygen we breathe, and serve as raw materials for many industrial products such as clothes, foot wears and so many others. Plants also provide raw materials for our buildings a...

ABSTRACT

Ficus vallis choudae is a plant widely spread in tropical Africa including Nigeria. It is said to be of value in ethnomedicine especially in the treatment of jaundice, gastrointestinal problems, giddiness and epilepsy. The anticonvulsant activity of methanol stem bark extract o...

ABSTRACT

Honeybee Propolis from Apis mellifera (Linn), has been used in ethno medicine as an emollient in the treatment of ringworm, measles, chickenpox and with reported biological activities, such as antitumor, antioxidant, immunomodulatory action and anti-inflammatory action among ot...

ABSTRACT

Solanum incanum Linn. and Solanum melongena Linn (Solanaceae) are both shrubs or trees found in the sub-Saharan Africa and the Middle East. Both are called „gauta‟ among the Hausa community of Northern Nigeria and „Tarku‟ among the Bura/Babar speaking people of Sout...

ABSTRACT

Daniellia oliveri is one of the most extensively utilized medicinal plants; it is a tree all of whose parts are used in Nigeria and some West African countries for the treatment of various ailments example the root is used as chewing stick. In the bid to standardize this plant,...

Abstract

Carissa edulis and Senna alata are plants found in Nigeria and some other tropical countries. In Nigeria, C. edulis and S. alata are used for the treatment of various ailments and diseases. In traditional medicine C. edulis is used for the treatment of skin infections, abdomina...

ABSTRACT

Spondias mombin belongs to the family Anacardiacae. All parts of the tree are reported to be medicinally useful. The fruit juice is drunk as a diuretic and febrifuge. The main aim of the study is to determine the diuretic activity and toxicity of methanol stem bark extract of S...

Abstract

The cellular immunity is often suppressed by infection, disease conditions and drug medication that are in continous association with mankind. Combretum micranthum is a plant known for its antioxidant, antimicrobial, anti-inflammatory and various other properties of immune boos...

ABSTRACT

Due to numerous problems associated with current treatment of trypanosomosis, there is increasing need to find effective drug against trypanosomosis ravaging sub-Saharan Africa from traditional medicinal herbs. This work is aimed at evaluating efficacy of stem-bark extracts of...

ABSTRACT

Asthma, which affects an estimated 300 million people worldwide, is an incurable health disorder of a major public health concern globally. The present orthodox therapy for asthma has several drawbacks including many undesirable side effects and high cost of management (especia...

ABSTRACT

Botanical extracts have shown appreciable achievement in controlling plant diseases. This became evident in this study when the potency of leaf extracts from Azadirachta indica, Carica papaya, Lawsonia inermis, Khaya senegalensis and Ziziphus spina- christi wer...

ABSTRACT

The goal of designing sustained release or controlled release delivery system is to reduce the frequency of dosing or to increase effectiveness of the drug by localization at the site of action, reducing the dose required or providing uniform drug delivery. Natural gums and pol...

ABSTRACT

Over the years, the use of plant-based molluscicides has received substantial consideration in the satisfaction for cost-effective alternatives to chemotherapy and synthetic molluscicides in schistosomiasis control. This study was aimed at evaluating the molluscicidal potential...

ABSTRACT

Cassytha filiformis, a leafless and perennial vine with small scales as a replacement of the leavesis currently being used in the treatment of various disease conditions including jaundice without standardization.Microscopical evaluation, chromatographic analysis (TLC, HPLC, LC...

ABSTRACT

Parquetina nigrescens is a plant with numerous ethnomedicinal uses in African traditional medicine practice. In the South Western part of Nigeria, the stems and roots are roasted, powdered then mixed with pap taken as memory enhancer and for its antiaging effect. This study the...

ABSTRACT

The qualitative and quantitative phytochemical analyses of 50 timbers of Nigeria were carried out. The physicchemical properties such as polymeric test, phytochemical test, solubility test, proximate analyses, saponification value, iodine value, acid value and peroxide value an...

ABSTRACT

Plants have provided a source for novel drug compounds, as plant derived medicines have made large contributions to human health and well-being. The aerial parts of Mitracarpus villosus were powdered, screened for phyto-compounds and the phyto- compounds detected were isolated....

1.0Background of Study

The Nigeria climate favours a great array of plant species many of which have varied medicinal and antimicrobial potentials (Adewusi, 1997; Adeuse-Poku et al., 2003; Ajebesone and Aina, 2004, Agyili et al., 2006). It is estimated that there are over 65,000 species...

Abstract

Ximenia americana is a plant used traditionally in northern parts of Nigeria for treatment of leprotic ulcers and mouth ulcers in addition to other medicinal uses. It contains flavanoids, saponins, tannins among others that has been reported to possess gastroprotective potentia...

ABSTRACT

The aim of this study was to investigate the ability of Adansonia digitata mucilage (ADM), a hydrophilic plant polymeric material to prolong the release of Metoprolol tartarate (MPT) from matrix tablet formulations compared with semi -synthetic polymer-HPMC60SH4000 matrices. Ph...

ABSTRACT

Post-harvest spoilage of fruits, particularly tomatoes and peppers, poses significant challenges to food security and economic sustainability in Nigeria. This study investigated the comparative antimicrobial efficacy of aqueous...